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Most likely not. Some people have a high tolerance to caffeine and can handle the intensity. However, Thriiv and caffeine for most will give one undesirable side-effects. The goal with Thriiv is to rehabilitate the mind, and by extension, the neuroreceptors that become abused when drinking coffee, caffeinated drinks, or taking other psychoactive substances. Thriiv already includes the optimal amount of each ingredient to keep the mind in a physiological harmony. It is not necessary to experiment bootleg neuroscience on yourself as we have already done the research and testing for you. If you want the best experience, and to be able to improve your mental ability over time, we suggest not mixing Thriiv with anything else mind altering such as coffee unless directed to do so by your doctor.