[vc_row][vc_column offset=”vc_col-md-offset-1 vc_col-md-10″][vc_custom_heading text=”Picamilon” font_container=”tag:p|font_size:75|text_align:center|color:%230c0c0c|line_height:1.3″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1545039975364{margin-bottom: 100px !important;}”][vc_row_inner css=”.vc_custom_1507817140639{margin-top: 60px !important;}”][vc_column_inner width=”1/2″ offset=”vc_col-md-5″][vc_custom_heading text=”Background” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289513107{margin-top: 0px !important;margin-bottom: 30px !important;}”][vc_column_text]Picamilon, also known as N-nicotinoyl-GABA, nicotinyl-gamma-aminobutyric acid, pycamilon, and pikamilon, is a great nootropic drug formed by a synthetic combination of niacin molecule (vitamin B1) and GABA. It is a naturally occurring or synthetic substance that inhibits or retards oxidation reactions. This supplement is most commonly used to specifically facilitate learning or memory, particularly to improve cognitive function, and for stress relief. It is capable of relieving pain without the loss of consciousness. This drug was first developed in the Soviet Union in 1969 and later further study was conducted in both Russia and Japan as a prodrug of GABA. However, Picamilon is not approved as a prescription drug in the United States. [1][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/2″ offset=”vc_col-md-offset-1 vc_col-md-5″][vc_single_image image=”10519″ img_size=”large” alignment=”center”][/vc_column_inner][/vc_row_inner][vc_custom_heading text=”Benefits” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289491888{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text]Millions of people around the world have been struggling with anxiety disorders that result in poor mental performance. Picamilon is a nootropic used for reducing anxiety disorders, stress relief, improved mental performance, and anti-aging effects. But Picamilon is most commonly known for its benefits that revolve around reducing anxiety (anxiolytic). Several studies show that Picamilon improves nervous control, recovery time after work, blood pressure and memory. Even it can help in brain trauma. The Russians use it for many different medical purposes such as relieving stroke victims, depression, asthenia, migraines and types of glaucoma. Picamilon is often compared to Phenibut which is also a GABAergic anti-anxiety supplement. But here lies a big difference and it is that Phenibut has a sedative effect whereas Picamilon does not.
The common health benefits of Picamilon include:

  • Reduces anxiety and depression [2]
  • Relieves stress [3]
  • Improves cognitive function [4][5]
  • Enhances learning and memory [5]
  • Enhances mental performance [6]
  • Is helpful for swimmers [7]
  • Helps with glaucoma [8]
  • Increases energy and extend endurance [9]
  • Relaxes brain and body [10]
  • Lowers blood pressure [11]
  • Relieves pain [12]
  • Increases of cerebral blood flow [13]
  • People report that it stabilizes mood, has anti-aging effects, is helpful for migraines, improves sleep

There are many nootropic users who are interested in taking Picamilon to promote their mood, alleviate stress and improve cognitive energy and focus. It may help people with anxiety, depression, sleep disorders or other mood disorders. It also enhances overall mental energy or stamina. Picamilon is also used by some people to help them overcome stress and shyness in social settings.[/vc_column_text][vc_custom_heading text=”How it works” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289481425{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text]Picamilon (N-nicotinoyl-GABA) is a synthetic amalgamation of GABA and niacin (vitamin B3). GABA is a neurotransmitter with relaxing and anti-anxiety effects. And niacin is a vitamin which is involved in DNA repair, fat and cholesterol synthesis, and widening of blood vessels. Picamilon can cross the blood-brain barrier and it does so by a special niacin analog pathway.
Being a GABAergic compound, Picamilon is thought to create a tranquil and easy-going state of mind in many people. Your brain uses the neurotransmitter GABA to promote relaxation and inhibit over-stimulation. Such effects are usually called as anxiolytic because they reduce anxiety and stress.
Picamilon, as a niacin precursor, can also contribute to increase energy metabolism in the brain and support neuron health. Being a vitamin of B complex group, niacin has a number of functions in both the nervous system and the gastrointestinal tract. The primary cognitive effect of niacin is as a cerebral vasodilator meaning that it increases blood circulation to the brain. By providing with more oxygen, glucose and other nutrients to your brain, Picamilon via niacin may result in upper levels of alertness and better concentration and mental stamina.[/vc_column_text][vc_custom_heading text=”Considerations” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289526095{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text]Like other nootropic supplement, Picamilon is usually safe and well tolerated by the majority of people. But it can have some adverse effects like lightheadedness, headache, nausea, irritability, low blood pressure, allergies and skin rashes or red flushing of the skin. Though they are not common, these side effects may be worse when Picamilon is taken more than recommended dosage.
You are advised to consult your doctor before using Picamilon with any other medications or anti-anxiety supplements, especially other compounds that work on the GABA receptors.[/vc_column_text][vc_custom_heading text=”Recommendations” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289542039{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text]There is no specific standard dose for Picamilon supplement. The dosage range greatly depends on your individual needs and purpose for using this supplement. However, a recommended dose range for mood boosting and energy support can be 50 – 100 mg per day. But a larger dosage of Picamilon such as 100 – 200 mg per day may be a suitable for anxiety and stress relief. Consult your physician or healthcare provider to determine an appropriate dosage for your need.[/vc_column_text][vc_custom_heading text=”Sources” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289552596{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text] 

  1. https://pubchem.ncbi.nlm.nih.gov/compound/34562-97-5#section=Pharmacology-and-Biochemistry
  2. https://www.ncbi.nlm.nih.gov/pubmed/16845932
  3. https://www.ncbi.nlm.nih.gov/pubmed/16971751
  4. https://www.ncbi.nlm.nih.gov/pubmed/9621180
  5. https://pubchem.ncbi.nlm.nih.gov/compound/Pikamilone#section=MeSH-Pharmacological-Classification
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056667/
  7. https://www.ncbi.nlm.nih.gov/pubmed/19803364
  8. https://www.ncbi.nlm.nih.gov/pubmed/23808185
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056667/
  10. https://www.ncbi.nlm.nih.gov/pubmed/16971751
  11. https://www.ncbi.nlm.nih.gov/pubmed/3709776
  12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918363/
  13. https://www.ncbi.nlm.nih.gov/pubmed/2707413

[/vc_column_text][/vc_column][/vc_row][vc_row disable_element=”yes” css=”.vc_custom_1593376599637{margin-top: 70px !important;margin-bottom: 50px !important;}”][vc_column offset=”vc_col-md-offset-1 vc_col-md-10 vc_col-xs-12″ css=”.vc_custom_1520108245936{margin-top: 5px !important;}”][vc_custom_heading text=”Where to Buy” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1520108399874{margin-top: 0px !important;margin-bottom: 30px !important;}”][vc_row_inner][vc_column_inner width=”1/2″][vc_single_image image=”1327″ img_size=”medium” alignment=”center” onclick=”custom_link” img_link_target=”_blank” lazy_loading=”true” link=”http://amzn.to/2CW71cv”][vc_custom_heading text=”Please use our link to make your amazon purchases as we use the commissions to help fund our research projects which in the end help you and the rest of the uplifted community. We do not have any affiliation with the company providing the product that we are referring you to. Our decision to find the best on Amazon is completely based on our scientific testing methods here at Nootripure Laboratories.” font_container=”tag:p|font_size:13|text_align:left|color:%23bfbfbf|line_height:1.2″ use_theme_fonts=”yes”][/vc_column_inner][vc_column_inner width=”1/2″][vc_column_text css=”.vc_custom_1520108323227{margin-top: -15px !important;}”]Here at Nootripure Laboratories we like to test supplements for potency as part of our market research and competitor analysis. We already did the research so we figured we would share with you the best products for each supplement. All SAMe supplements are artificially manufactured as they can only be produced by the body. So all of them are generally similar. In this case we suggest going with a trusted brand that actually puts in the bottle what they put on the label. We get commissions on any SAMe supplement you buy on Amazon, but we would recommend the one in the link provided.[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row]