Sulbutiamine

What is Sulbutiamine

Sulbutiamine is called the enhanced version of Vitamin B1. Actually, it is a synthetic derivative of thiamine also known as vitamin B1 and sold under the market name Arcalion. It is composed of two modified thiamine molecules and crosses the blood-brain barrier more effectively than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain. Sulbutiamine provides a variety of cognitive benefits, including helping improve memory and learning. It improves erectile dysfunction and reduces psycho-behavioural inhibition. Sulbutiamine demonstrated evidence of modulatory effect on dopaminergic and glutamatergic cortical transmissions. It is also used by people with asthenia.

Sulbutiamine Health benefits

Sulbutiamine is known as the man-made chemical which is similar to the B vitamin thiamine. Thiamine dissolves in water, but sulbutiamine dissolves in fats. It is able to increase thiamine levels in your brain, and also considered to be used as a stimulant in athletes.[2] As a nootropic, sulbutiamine helps improve cognitive function, memory, learning capacity, decision-making, concentration, focus, and more. It also enhances your energy levels and general brainpower. It improves your memory, depression, shyness, fatigue and even erectile dysfunction. The common health benefits of Sulbutiamine include:Improves cognitive function [3] Increases memory [4] Enhances learning capacity [5] Improves mood [6] Relieves fatigue [7] Reduces depression [8] Improves erectile dysfunction [9] Helps people with Alzheimer’s disease [10] Increases athletic performance [11] Helps with diabetes [12] Increases hippocampal cholinergic activity [13]Sulbutiamine is most well-known for its benefits for improving memory when people take it as a regular basis. The users have noticed an improvement in both their short and long-term memory skills.

How does it work?

How sulbutiamine works in the brain has not been fully understood. When a Sulbutiamine dosage is ingested orally, it is absorbed from your intestines and then circulates through the blood to your brain tissue. After penetrating the blood-brain barrier, it is broken down into Vitamin B1 and certain related esters. However, it seems to have various effects on the brain that might improve memory and reduce feelings of weakness. Sulbutiamine is a lipophilic compound with the ability to dissolve in cross cell membranes or fatty tissue. Its designed works for it to act in the brain though it is not considered to have psychostimulant properties. It is basically a nootropic vitamin; thiamine is simulated by sulbutiamine to a certain extent. One important thing is that sulbutiamine appears to be beneficial for its enhanced effects on the neurons of the brain, specifically in their basic transmission and communication abilities. Sulbutiamine produces great effects on these vital brain activities, namely glutamate, dopamine, and acetylcholine.

Consideration and recomendation

Sulbutiamine is generally considered very well-tolerated. But there are some side effects to be aware of when it is taken for a longer time. Sometimes, people report developing eczema-like symptoms and skin rashes. Some people taking sulbutiamine have reported nausea, headache, tiredness, and inability to sleep.
It is also known to have a negative outcome in some people with a bipolar mood disorder, as well as difficulties in falling asleep. If you are pregnant or breastfeeding, stay on the safe side and avoid taking sulbutiamine. Consult your doctor before starting any supplement.

The suitable dosage range of Sulbutiamine depends on several factors such as the user’s age, health, and several other conditions. Still, a recommended Sulbutiamine dosage can be 400 mg to 1,000 mg per day. You should split higher doses, with one dose in the morning, and the other early afternoon.
As Sulbutiamine may cause tolerance problems, if you want to take it for extended periods, you may find it beneficial to cycle on and off the supplement. For example, take Sulbutiamine for 5 days, and take 2 days off before your next dose.
There are some who frequently take Sulbutiamine is a nootropic stack with other supplements to boost energy levels and general brainpower.

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