Nicotine
Whats is Nicotine?
Nicotine is a powerful parasympathomimetic stimulant drug with nootropic mechanisms of action and an alkaloid found in the nightshade family of plants. It is an active but addictive ingredient found in cigarettes and most tobacco products. There are certain nicotinic receptors in the brain for the neurotransmitter acetylcholine as they are also stimulated by interaction with nicotine. Though we all are aware that nicotine is the primary reason for addiction to smoking cigarette or other tobaccos, Nicotine may actually have medicinal benefits for a number of conditions including performance-enhancing effects on cognition, alertness, and focus.[1]
Nicotine health benefits

How Nicotine works
Nicotine reduces body weight by increasing energy expenditure and inhibiting the expected compensatory increase in caloric intake.[5] Though some people say that nicotine may be helpful for enhancing creativity, two recent studies involving nicotine’s effect on creativity found the relationship to be inconsequential.
Recomendations?
Source
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710300/
Carl V. Phillips and Paul L. Bergen, Tobacco Harm Reduction 2010: a yearbook of recent research and analysis
http://www.guidetopharmacology.org/GRAC/FamilyIntroductionForward?familyId=76
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1601132/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195407/
https://www.ncbi.nlm.nih.gov/pubmed/12151749
https://www.ncbi.nlm.nih.gov/pubmed/11406005
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288130/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758075/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466669/
https://www.ncbi.nlm.nih.gov/pubmed/22813222
http://www.sciencemag.org/news/2001/07/nicotine-grows-new-blood-vessels
https://www.ncbi.nlm.nih.gov/pubmed/11861793