Hops have traditionally been used for centuries to flavor and preserve beer. The bitter, aromatic taste of beer is mostly due to the hops substance. Hops are commonly used orally for anxiety, sleep disorders such as the inability to sleep (insomnia) or disturbed sleep because of rotating or nighttime work hours (shift work disorder), restlessness, tension, excitability, attention deficit-hyperactivity disorder (ADHD), nervousness, irritability, and symptoms of menopause among other uses.[2]
Researches demonstrate that hops exert significant antidepressant effects through their interaction with serotonin and melatonin receptor subtypes, which lead to dampened stress levels and improved relaxation and sleep patterns.[3][4]
The common health benefits of hops include:

• Reduce depression, anxiety and stress [5]
• Relieve insomnia and improves sleep quality [6]
• Are used as anxiolytics and hypnotics [7]
• Help people with attention deficit-hyperactivity disorder (ADHD) [8]
• Relieve menopausal symptoms [9]
• Help people who have Alzheimer’s disease [10]
• Improve cognitive function [11][14]
• Improve relaxation [12]
• Enhance estrogen levels [13]
• Helps people fight cancer [15]
• Improves mood [17]

The flavonoid compound called xanthohumol, which is contained in hops may have antiviral, anti-clotting, anti-inflammatory, and anti-tumor activity. This dietary supplement has been used by women as a sleep aid and for postmenopausal symptom relief. In addition to its efficacy for menopausal symptoms, hops can also modulate the chemical estrogen carcinogenesis pathway and potentially protect women from breast cancer.[16] Again, a standardized mix of sedative herb Valerian and Hops, called Ze91019, is used as a sleep aid. Moreover, hops have an anti-anxiety effect, for which you actually feel less tense after drinking hoppy beer.