CDP-choline (citicoline) has shown cholinergic and neuroprotective actions. It is a great nootropic supplement best known for its ability to enhance memory.

It’s true that choline may not be one of the most superb or popular topics in the media today regarding health and wellness. It is, actually, a nutrient that is vital for overall health.

CDP-choline has been shown as a prodrug used for improving brainpower. Besides improving memory, it helps people with a variety of neurodegenerative disorders. CDP-choline has been used for, particularly in relation to ischemic stroke, head trauma, age-related cognitive deterioration, and Alzheimer’s Disease.[4]

CDP-choline is hydrolyzed in the small intestine to form choline and cytidine, which are easily absorbed and dispersed throughout the organism. It is shown in a study that choline and cytidine can cross the blood-brain barrier (BBB), where they are re-synthesized into CDP-choline.

Experience in humans shows that cytidine is metabolized into the amino acid uridine, which can also cross the BBB and help support the biosynthesis of phospholipids.[5]
The common health benefits include:

1. Improves cognitive performance [6]
2. Improves learning and memory [7]
3. Enhances concentration [8]
4. Increases mental energy [9]
5. Shown to have an effect on people who have attention-Deficit
6. Hyperactivity Disorder (ADHD) [10]
7. Increases working memory [11]
8. Shown to have an effect on Alzheimer’s disease [12]
9. Shown to have an effect on patients with cerebral insufficiency, chronic cerebrovascular disease, and dementia [13]
10. Shown to have an effect on Parkinson’s disease [14]
11. Shown to have an effect on acute ischemic stroke [15]
12. Improves visual evoked potentials in some glaucoma patients [16]

CDP Choline is a powerful nootropic supplement and supplementing with a choline source such as CDP Choline can help amplify and enhance the effects of other nootropic supplements. It works synergistically with racetam class nootropics, knowingly strengthening the effects of memory enhancers such as Piracetam.[17]