Nootropics to Improve Your Mood

Introduction

It seems that depression, fatigue, anxiety, fear, or exhaustion are always haunting us and we are frequently trying to get rid of them by taking different mood-enhancing drugs. Some recent research shows that those mental issues can have many possible causes like mood disorder, genetic problems, stressful events, prescription medications and medical problems. And there are nootropics that work here effectively. With the supplementation of the suggested nootropics here, you just feel uninterrupted advancement in your daily activities.
Actually, nootropics are well-known for their effectiveness for enhancing cognitive functions, brain power and also for increasing both physical and mental energy levels. Nootropics are mainly used to help with learning and studying, boosting memory capacity, speeding up information recall, and helping overcome cognitive impairments. Besides improving mental cognition, recent research provides details on how nootropics can also benefit your mood and sense of well-being. Yes, you’ll find our suggestions for the best nootropics for better mood. But, first, let’s see how these nootropics or brain supplements work to improve your mood.

How Do Nootropics Work for Better Mood?

There are several neurotransmitters, amino acids, hormones and other neurochemicals working both inside and outside our neurons. And the interactions of those neurochemical reactions frame a highly dynamic system responsible for your mood, perception and experience. However, symptoms of depression and other mood related issues in your brain and body may be similar to or completely different from the person next to you. Again, two neurotransmitters, namely – inhibitory and excitatory serve two different functions. While excitatory neurotransmitters work to stimulate the brain, inhibitory neurons work to create balance and calmness in the brain, a crucial function of natural ADHD medications. Feelings of stress, anxiety, and depression can occur if excitatory neurotransmitters are overactive. This over-activity may quickly exhaust the supply of inhibitory neurons creating an unbalanced chemical environment in your brain. Active inhibition of excitatory neurotransmitters helps to achieve mood stabilization and lessen the feelings of depression and anxiety. That’s why some drugs or supplements are needed to increase the presence of inhibitory neurotransmitters in the brain and enhance your mood.

Recommeded Nootropics for Your Better Mood

The mood-boosting nootropics and supplements suggested below can play a role in maintaining that all important balance you need.
 

  1. Noopept

    Noopept, a peptide-derived nootropic related to the racetam-family, is said to be much more potent than Piracetam. However, its mechanism of action in your brain is similar to other racetams. You can get away with much smaller daily dosage of Noopept to achieve the same mood-boosting effects. The daily recommended dosage for Noopept is around 10mg to 30mg.[18] Piracetam requires 4 to 8 grams per day to achieve similar cognitive enhancement results. Noopept stimulates dopamine, nicotinic and serotonin receptors and helps boost cognition, memory, logical thinking, reflexes and mood. It is also very much effective in treating depression and bringing a joyful mood.[1]

 

  1. Ashwagandha

    Ashwagandha is an adaptogen that has been used for millennia to relieve anxiety,[19] fatigue, restore energy and boost focus.[20] Ashwagandha has been shown in clinical studies as a supplement to repair and even reverse damage caused in the brain caused by chronic anxiety and stress. The main action is that the withanolide reduce cortisol release causing the inhibition of stress. A study shows that the use of Ashwagandha as a mood stabilizer in clinical conditions of anxiety and depression.[2]

 

  1. Phenibut

    Phenibut is thought as a GABA agonist and primarily binds to the GABA-b GABA-a receptor agonists include alcohol and benzodiazepines. It is very effective in reducing anxiety and may have a sedative effect. It is very helpful to reduce depression; improve mood, cognitive function and motivation.[21] The main benefit of Phenibut is that it has anxiety reducing (anxiolytic) compound [3] and many users use Phenibut for increased mood (euphoria even).[4]

  1. Omega-3 Fish Oil

    Omega-3 fatty acid which is also more commonly known as fish oil has exceptional qualities of reducing depression. There are two types of omega-3 supplements to consider – EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). DHA is mostly known for supporting cognitive function by improving communication between neurons in your brain. Some studies show that EPA can be much more useful for reducing symptoms of anxiety, bipolar disorder, and depression. Epidemiological, biological and clinical studies implicate that omega-3 fatty acids are important in the development and treatment of various mental illness, including mood and anxiety disorders.[5]

 

  1. Phosphatidylserine

    Phosphatidylserine (PS) is a phospholipid that plays an important role in the growth and maintenance of neurons. Since the main structural force behind our cell membranes, PS is vital for cell-to-cell communication and healthy brain function. This phospholipid is well-known among nootropic users for its ability to improve focus, mental stamina, and memory. Almost like fish oil, Phosphatidylserine provides with many benefits outside of neuroprotection and nootropic properties. Studies have shown that in young adults, with neuroticism scores above rather than below the median, the taking of 300mg Phosphatidylserine (PS) each day for a month was associated with feeling less stressed and having a better mood. The study for the first time reports an improvement in mood following PS supplementation in a sub-group of young healthy adults.[6]

 

  1. Aniracetam

    A member of the racetam-family of nootropics, Aniracetam is one of the most effective nootropics for reducing depression and works with dopamine D2 and D3 receptors in your brain, and desensitizes AMPA (glutamate) receptors. Aniracetam was developed as a more powerful analog of the nootropic drug Piracetam and is said to be 3-6 times more effective than Piracetam and has greater oral bio-availability, in part because of the fact that it is fat soluble. Aniracetam has also been used in the treatment of cognitive disturbances, mood and motor performance in patients with stroke and Alzheimer’s disease.[7]

Aniracetam has immense health benefits which have made this supplement different from others. Aniracetam improves cognitive performance, increases memory, concentration, mental endurance, focus, memorization, and visual perception.[22] It enhances learning capacity, creativity, and verbal fluidity. It also reduces anxiety, stress, depression, promotes mood, motivation, sleep and wakefulness. Aniracetam prevents ADHD, autism, negative symptoms of schizophrenia.[8][9]

  1. L-Tyrosine

    L-Tyrosine, a nonessential amino acid, plays a vital role in the production of neurotransmitters (catecholamines) dopamine and noradrenaline. Some protein-rich foods like turkey, chicken, fish, yogurt, milk, cheese, avocados, and almonds contain L-Tyrosine. Studies have shown little to no effect of L-Tyrosine for mood improvement in normal individuals. L-Tyrosine supplements have many benefits including elongated sleep deprivation, stress-induced weight loss, extreme fatigue, or significant life stress (such as divorce, bankruptcy, or death).[23] When acute stressors occur, there may be a depletion of noradrenaline and other neurotransmitters related to mood. Once L-Tyrosine is metabolized, it may influence catecholamine synthesis when the body is under immense stress. A study noted improvements (relative to placebo) on global ratings of mood and happiness and cognitive function.[10]

 

  1. L-theanine

    L-theanine is an amino acid (a building block for proteins) found ingreen tea. This natural nootropic has been researched for its ability to support brain health, reduce anxiety and depression and enhance mood and focus.[11]

People use L-theanine for reducing anxiety and high blood pressure, for the relief from Alzheimer’s disease, and for making cancer drugs more effectively.[12] L-theanine has a lot of different benefits for mood, cognitive function and general health. L-theanine enhances the production of GABA, an amino acid and neurotransmitter, which works to calm the mind and relax the body by relieving over-excited stress signals in the brain.
 

  1. Sulbutiamine

    Sulbutiamine is a synthesized form of Vitamin B1 (thiamine) which easily crosses the blood-brain barrier.[24] As a nootropic, it is taken to improve mood, memory and motivation. A study found that 2 months after supplementing with thiamine, participants were more clearheaded, felt more composed and energetic, reaction times improved, and mood was better.[13]

 

  1. John’s Wort

    St. John’s wort is a plant that has traditionally been used for mood disorders and wound healing. Nowadays it is used mostly as a treatment for anxiety, depression and stress.[25] St. John’s wort is beneficial to treatment of mental health problems. It has antibacterial, antioxidant, and antiviral properties. For its anti-inflammatory properties, St. John’s wort has been applied to the skin to help heal wounds and burns.[14] Recently studies conducted to investigate the nootropic effect of St. John’s wort in normal human subjects. Some studies in animals have suggested that St. John’s wort may have memory-enhancing effects.[15]

  1. Inositol

    Inositol is a psuedovitamin that is used as a brain supplement for enhancing the mood and energy levels. It works particularly well in women to relieve anxiety, binge eating, PMS and more. It appears to be quite effective in treating insulin resistance and PCOS with standard doses.[1] The Natural Medicines database has rated Inositol as Possibly Effective for improving lithium-induced side effects, OCD, panic disorder, polycystic ovary syndrome, and respiratory distress syndrome. It is believed that there are a number of brain benefits from taking Inositol supplements, including improved mood, more focus, and better thought processing.[16]

 

  1. 5-HTTP

    5-HTP, a “natural antidepressant”, is an amino acid naturally produced in your body.  It is the precursor needed to produce the ‘feel-good’ neurotransmitter serotonin. It is used to reduce depression, but  a summary published by the Alternative Medicine Review noted a lack of evidence for ‘loading’ precursors to reduce depression.[17]

5-HTP is the immediate precursor to serotonin, meaning it converts directly into this mood stabilizing neurotransmitter once it enters your brain. Replenishing serotonin from age-related depletion can contribute to feelings of happiness and well-being, relaxation, and calmness, as well as an improved mood.
 

  1. Modafinil / Adrafinil

    Both Modafinil and Adrafinil are eugeroics, mostly known as wakefulness-promoting drugs. Fladrafinil also has similar cognitive effects to those listed for both Adrafinil and Modafinil. The cognitive effects include improved memory and recall speed as well as a possible increase in learning capacity. As the attention period is also expanded, you will have the ability to concentrate and focus. You will also find it easier to engage in common tasks like reading, writing, talking, and giving presentation. These supplements reduce fatigue and diminish symptoms of ADHD in children.[26] They also increase wakefulness and improve focus and mood, and also increase dopamine.[27]

Final Thoughts on the Nootropics as Enhancing Drugs for a Better Mood

Nowadays, the conscious people go for nootropics for better mood as they are a strong alternative to many antidepressant medications currently prescribed by doctors. The above list of nootropic supplements can be beneficial to boost your mood, increase your energy levels, relieve symptoms of depression or anxiety, and help decrease stress. But you have to be slightly cautious while taking any medications. Though nootropics are generally without any serious side effects, you have to research each nootropic including side effects and interactions before using nootropics.
 

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