CoQ10

Background

CoQ10, the abbreviated form of Coenzyme Q10 and also known as ubiquinone as well as ubidecarenone, is an extremely strong antioxidant existing within our mitochondria fighting off free radicals. The CoQ10 is found through food sources like oily fish such as sardines as well as beef and peanuts but the supplement has profound effects on our levels of energy, stamina, organ health, immune system functionality and more. The two types of CoQ10 used in supplements are ubiquinone (oxidized form) and ubiquinol (reduced form). The most commonly available and the cheapest form of CoQ10 is ubiquinone, but ubiquinol is superior to ubiquinone because the body doesn’t have to convert ubiquinol into a usable form – it is already ‘body-ready’.

Benefits

CoQ10 or Coenzyme Q10 is a very effective antioxidant and natural nootropic for brain health. It helps create energy in the mitochondria, which in turn deliver the increased energy supply to other parts of the body and brain. CoQ10 is vital for energy production within the heart, liver and muscles and helps convert fat, carbohydrates and protein molecules into the fuel that is used by cells throughout our body. With immense health benefits, CoQ10 is used for more energy, better cardiovascular health and more fuel for energy-demanding organs such as the brain. In addition, CoQ10 benefits include –

  • Enhance blood flow and protect the blood vessels [5]
  • Reduces fatigue and boosts stamina [6]
  • Helps people who have cognitive disorders, including Parkinson’s disease [7]
  • Helps people who are suffering migraines [8]
  • Increases physical performance [9]
  • Enhances focus [10]
  • People report as it increases creativity
  • Improves heart health [11]
  • Defends against free radicals and typical signs of aging [12]
  • Restores the power of antioxidants, including vitamin E and vitamin C [13]

One clinical study found that patients taking daily CoQ10 supplements within 3 days of a heart attack are less likely to get affected by heart attack for the next time. It is also helpful for high blood pressure, high cholesterol, diabetes and gum disease. CoQ10 helps increase sperm motility, improving male fertility [1][2]

How it works

CoQ10 or Coenzyme Q10 is a type of substance similar to a vitamin. It is found in every cell of your body. Your body makes CoQ10, and the cells use it to produce energy that your body needs for cell growth and maintenance. CoQ10 also functions as an antioxidant, which protects the body from damage caused by harmful molecules.[3]
CoQ10 is involved in cellular energy metabolism and mitochondrial function as a cofactor in oxidative respiration for the Krebs cycle and ETC. it is also an important fat-soluble anti-oxidant.
Because of its involvement in ATP synthesis, CoQ10 affects the function of all cells in the body, especially those with high-energy demand, making it essential for the health of all tissues and organs. CoQ10 is our only lipid-soluble antioxidant synthesized endogenously and efficiently prevents oxidation of proteins, lipids and DNA. The primary role of CoQ10 in mitochondrial bioenergetics and its well-acknowledged antioxidant properties constitute the basis for its clinical applications, although some of its effects may be related to a gene induction mechanism.[4]

Considerations

CoQ10 is considered to be safe and has been used in the medical field for many years. But in some cases, it may have some side effects such as mild insomnia, elevated levels of liver enzymes, rashes, nausea, upper abdominal pain, dizziness, sensitivity to light, irritability, headache, heartburn and fatigue. In case of such situation, or being pregnant or breast-feeding condition, you are recommended to consult with your doctor.

Recommendations

CoQ10 is an adult supplement. According to a survey done by ConsumerLab.com including over 50 CoQ10 products tested, the suggested daily serving size ranges from 30 milligrams to 1,000 milligrams daily. Most experts also recommend that you can take at least 200 milligrams daily to experience benefits. However, those on statins or weighing over 200 pounds might consider a higher dose.

Sources