Best Nootropics for ADD & ADHD: 10 Alternatives to Adderall


Attention Deficit Disorder with or without hyperactivity (ADD, ADHD) is not just a childhood disorder, whereas the symptoms of ADHD begin in childhood and can continue through adolescence and adulthood. In fact, it causes an extra obstacle for both students and teachers. Though there are effective medications for alleviating attention deficits, these medications usually carry with them the possibility of addiction and dependence.[1]

Attention Deficit Disorders

Attention deficit disorder (ADD) or Attention deficit hyperactivity disorder (ADHD) is a brain disorder marked by an ongoing pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development. The two most commonly used drugs for the treatment of ADHD in children and adolescents are Adderall (amphetamine / dextroamphetamine) and Ritalin (methylphenidate). However, knowing of potential side effects [8] of such drugs, many people look for safe medications for their own children or themselves. For this reason, conscious people use the most common nootropics like racetam drugs, modafinil and noopept, as alternatives to amphetamines.
These nootropics have been demonstrated to have positive effects on cognition. But it is necessary for you to personalize treatment, evaluating whether the course of treatment is actually working for you. Keep in mind that the effectiveness of these nootropics can vary person to person. Keeping a journal about the dosage and administration of nootropics can help you greatly.
Many nootropics are well-known for their ability to improve cognition, motivation, and concentration.[2] However, always consult your doctor before making adjustments to any medication.

Top 10 Nootropics for ADD & ADHD

According to scientific studies and our anecdotal experience, we have selected the best nootropics for Attention Deficit Disorder with or without Hyperactivity. Hope you will be benefited much.


Piracetam is known as the parent compound of the racetam family of nootropic drugs. It has a history of being used in the condition of dementia, Alzheimer’s Disease and other cognitive diseases that come with old age.[9] According to a meta-analysis on human studies, piracetam helps improve general cognition [10] when supplemented by individuals in a state of cognitive decline, such as the kind that comes with aging as well as provides a mild boost to brain function. Though piracetam does not seem like an ideal alternative treatment for attention deficits, a small study mentions a combination of atomoxetine (an ADHD medication) and Piracetam.


Noopept is an excellent nootropic that said to be 1,000 times stronger than Piracetam [11] and also much faster effects but much lower dosage than Piracetam. It is very popular for its ability to improve cognition and increase focus and concentration for extended periods of time.[12] Noopept is very popular among students as it assists with memory formation, but with extra edges that are memory consolidation and memory recovery. Experts at the Second International Congress on ADHD noted that noopept may be a very good alternative medication for attention deficits.


Phenylpiracetam is a derivative of piracetam but more effective in improving memory and learning compared to piracetam and other nootropic supplements, and by improving cerebral processing, it benefits cognitive function as well as improves focus.[13] A 100 mg of phenylpiracetam is comparable to about 800 mg dose of piracetam. However, you can’t use it indefinitely as tolerance develops relatively quickly. To cycle with other nootropics is useful,


Pramiracetam is also a derivative of piracetam and very potent as a cognitive enhancer. But it is not as well researched as some of the more popular racetams. Pramiracetam demonstrates an ability to help reverse scopolamine-induced attention deficits in humans, and anecdotal experiences on the web show that it’s effective in young subjects with ADD, but not in those with normal “baseline” performance.


Memantine is a commonly used drug to treat cognitive decline, for instance, moderate and severe Alzheimer’s Disease.[14] Memantine works on the glutamatergic system as an antagonist to NMDA receptors that work to combat excitotoxicity. It doesn’t allow the development of tolerance to a number of substances, including stimulants, caffeine, cannabis, alcohol and so on. Thus it’s usually combined with stimulants to reduce their neurotoxic effects as well as reducing tolerance to the positive effects of Adderall and Ritalin. A study found that Memantine was fairly beneficial for alleviating symptoms of ADHD, but concluded that there is not enough evidence to draw any real conclusions.[3] For this, Memantine is used in low doses alongside another substance on this. So, proceed with caution because Memantine acts as a dissociative at supratherapeutic doses,


Modafinil is a nootropic to increase alertness and energy levels. It has the benefits for cognition via increasing levels of stimulatory neurotransmitters in the brain. Several studies have found that modafinil enhances cognitive performance and working memory, increases alertness, attention and focus, and mood and reduces fatigue and diminishes symptoms of ADHD in children.[15] A study conducted on children found that 48% of the participants felt a significant improvement in attentive skills while on modafinil.[4]


Selegiline (L-deprenyl) is a substituted phenethylamine drug normally used in the treatment for Parkinson’s disease [16] and dementia, as well as for depression. A study done on a small group of 28 children with ADHD demonstrates the treatment effects of selegiline in comparison to methylphenidate. It is seen that the children treated with selegiline displayed fewer symptoms of ADHD than those treated with methylphenidate while also displaying fewer side effects.[5]


Cholinergic dysfunction is associated with multiple brain disorders including Alzheimer’s Disease, addiction, schizophrenia and Attention-Deficit Hyperactivity Disorder (ADHD).[6] Choline is a crucial nutrient and precursor to acetylcholine that can be obtained in various ways from different foods and also from supplements. CDP-Choline and Alpha GPC are generally considered to be the two most effective sources of Choline for nootropic use.


L-Tyrosine is an amino acid that works as a precursor to the neurotransmitters noradrenaline and dopamine. A study found that supplementation of both Tyrosine and 5-HTP (a serotonin precursor) helped improve ADHD symptoms in 77% of the participants.[7] The supplement can help improve attention deficits by increasing levels of neurotransmitters that play a significant role in attention.


Uridine is a nucleotide base that has been found to improve memory, attentiveness, cognition, and learning.[17] Cognitive benefits of Uridine’s occur with its supplementation alongside other nootropics, such as racetams and noopept. It is considered to be a safe substance to combine with other nootropics and medications.

Final Consideration

You will find many nootropics, pharmaceuticals, and supplements that show significant promise for treating attention deficits. However, we recommend you THRIIV, a blend of powerful adaptogens combined with stimulating herbs and nootropic compounds that is specifically formulated to increase creativity, cognition, memory, focus and uplift your mood. THRIIV is alone more effective for the treatment of ADD or ADHD than all these supplements can do separately.