[vc_row][vc_column offset=”vc_col-md-offset-1 vc_col-md-10″][vc_custom_heading text=”Adrafanil” font_container=”tag:p|font_size:75|text_align:center|color:%230c0c0c|line_height:1.3″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1526560304957{margin-bottom: 100px !important;}”][vc_row_inner css=”.vc_custom_1507817140639{margin-top: 60px !important;}”][vc_column_inner width=”1/2″ offset=”vc_col-md-5″][vc_custom_heading text=”Background” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289513107{margin-top: 0px !important;margin-bottom: 30px !important;}”][vc_column_text]Adrafinil, (the chemical name for the smart drug is CRL-40028, and also known by brand or trade name as Olmifon), is a pro-drug for the cognitive enhancer modafinil and synthetic nootropic compound not found in any dietary source. Adrafinil is a eugeroic closely related to modafinil and supplementation of adrafinil promotes wakefulness and alertness as well as leads to increased concentrations of modafinil in the body. French pharmaceutical company Lafon Laboratories discovered it in the 1970s to promote alertness, attention, wakefulness, mood, and other parameters, particularly in the elderly people. But, later Adrafinil had been prescribed throughout Europe mainly as a treatment for narcolepsy, apnea and other sleep disorders that cause excessive daytime sleepiness.[1][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/2″ offset=”vc_col-md-offset-1 vc_col-md-5″][vc_single_image image=”2555″ img_size=”large” alignment=”center”][/vc_column_inner][/vc_row_inner][vc_custom_heading text=”Benefits” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289491888{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text]Since it is a wakefulness-promoting smart drug, you can make a successful use of Adrafinil as a nootropic for promoting wakefulness for people who find themselves feeling overly sleepy and tired throughout their day due to sleep disorders like sleep apnea and narcolepsy.
The cognitive effects Adrafinil include improved memory and recall speed as well as a possible increase in learning capacity. As the attention period is also expanded, you will have the ability to concentrate and focus. You will also find it easier to engage in common tasks like reading, writing, talking, and giving presentation. Students use adrafinil as a study pill, for alertness and staying awake for all-night cram sessions before an important exam. The benefits of Adrafinil include –

  • Promotes Wakefulness [4]
  • Increases Alertness [5]
  • Reduces Stress [6]
  • Heightens Concentration and Focus [7]
  • Improves Memory and Recall [8]
  • Enhances Learning Capacity [9]
  • Increases Athletic Performance [10]
  • Enhances Mood [11]
  • Improves Motivation [12]

Adrafinil acts as a central nervous system stimulant, relieving you of fatigue and increasing energy. However, Adrafinil does more than just fighting sleepiness; its potential cognitive benefits include improved memory, heightened focus over longer periods, and even increased learning capacity. It is also helpful for some people in promoting a sense of well-being, reduction of stress, and enhanced excitement or pleasure. This may be related to the stimulation of dopamine receptors which occurs with Adrafinil usage.[/vc_column_text][vc_custom_heading text=”How it works” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289481425{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text]

Adrafinil is a pro-drug; it is primarily metabolized in vivo to modafinil, resulting in nearly identical pharmacological effects. Unlike modafinil, however, it takes time for the metabolite to accumulate to active levels in the bloodstream.[2]


Though the accurate chemical mechanisms of Adrafinil are not completely apparent, researchers assume that in its metabolized form it acts as an adrenergic receptor agonist. One of its main actions can be the increased production and release of the neurotransmitter hypocretin, which in turn can trigger the increased production of dopamine, histamine, and norepinephrine. These neurotransmitters and hormones are considered directly related to wakefulness and energy levels, which mostly explains stimulant properties of Adrafinil.

The potent mood improving and cognitive enhancing effects of Adrafinil are considered to be made by several actions, including the positive modulation of glutamate receptors and inhibiting the breakdown of glutamate. This can result in increased neuronal communication that improves memory and focus and creates better general cognitive function. It also helps stimulate the release of serotonin, which improves mood by helping lessen anxiety. It may also inhibit the breakdown of dopamine, a neurotransmitter that plays an important role in the brain’s excitement and pleasure centers as well as emotional responses.[3]

[/vc_column_text][vc_custom_heading text=”Considerations” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289526095{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text]Adrafinil is a novel stimulant that fewer adverse effects associated with other psychostimulants. However, those side effects can be ranging from mild to more severe in nature such as the users may experience headaches, dizziness, stomach discomfort, and nausea while taking Adrafinil.
Even long-term usage could potentially affect liver function.  You are recommended to speak to a doctor before using this or any other smart drug to make sure you are healthy enough to use this product.[/vc_column_text][vc_custom_heading text=”Recommendations” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289542039{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text]

Dosage recommendations vary from person to person, but a range of 150 to 300 mg daily is widely accepted as safe and effective. Adrafinil being a very powerful nootropic, you are suggested to give your body a chance to adjust by starting with a lower dosage of adrafinil and gradually increase it as needed.

Because of its powerful wakefulness-inducing properties, it is also recommended not to take adrafinil on an empty stomach and take in the morning to allow for normal night’s sleep.

[/vc_column_text][vc_custom_heading text=”Sources” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1517289552596{margin-top: 50px !important;margin-bottom: 30px !important;}”][vc_column_text] 

  1. https://examine.com/supplements/adrafinil/
  2. https://pubchem.ncbi.nlm.nih.gov/compound/adrafinil#section=Pharmacology-and-Biochemistry
  3. http://onlinelibrary.wiley.com/doi/10.1111/j.1527-3458.1999.tb00100.x/epdf
  4. https://www.ncbi.nlm.nih.gov/pubmed/15252267
  5. https://www.ncbi.nlm.nih.gov/pubmed/10880681
  6. http://www.studydrugs.net/Adrafinil-Review.html
  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286657/
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341927/
  9. https://www.ncbi.nlm.nih.gov/pubmed/10880682
  10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846503/
  11. https://www.ncbi.nlm.nih.gov/pubmed/11191710
  12. https://www.ncbi.nlm.nih.gov/pubmed/10880682

[/vc_column_text][/vc_column][/vc_row][vc_row disable_element=”yes” css=”.vc_custom_1530138609991{margin-top: 70px !important;margin-bottom: 50px !important;}”][vc_column offset=”vc_col-md-offset-1 vc_col-md-10 vc_col-xs-12″ css=”.vc_custom_1520108245936{margin-top: 5px !important;}”][vc_custom_heading text=”Where to Buy” font_container=”tag:p|font_size:50|text_align:left|color:%23c1c1c1|line_height:1.4″ google_fonts=”font_family:Open%20Sans%3A300%2C300italic%2Cregular%2Citalic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1520108399874{margin-top: 0px !important;margin-bottom: 30px !important;}”][vc_row_inner][vc_column_inner width=”1/2″][vc_single_image image=”1327″ img_size=”medium” alignment=”center” onclick=”custom_link” img_link_target=”_blank” lazy_loading=”true” link=”http://amzn.to/2CW71cv”][vc_custom_heading text=”Please use our link to make your amazon purchases as we use the commissions to help fund our research projects which in the end help you and the rest of the uplifted community. We do not have any affiliation with the company providing the product that we are referring you to. Our decision to find the best on Amazon is completely based on our scientific testing methods here at Nootripure Laboratories.” font_container=”tag:p|font_size:13|text_align:left|color:%23bfbfbf|line_height:1.2″ use_theme_fonts=”yes”][/vc_column_inner][vc_column_inner width=”1/2″][vc_column_text css=”.vc_custom_1520108323227{margin-top: -15px !important;}”]Here at Nootripure Laboratories we like to test supplements for potency as part of our market research and competitor analysis. We already did the research so we figured we would share with you the best products for each supplement. All SAMe supplements are artificially manufactured as they can only be produced by the body. So all of them are generally similar. In this case we suggest going with a trusted brand that actually puts in the bottle what they put on the label. We get commissions on any SAMe supplement you buy on Amazon, but we would recommend the one in the link provided.[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row]